[HTML][HTML] Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall
A Gronchi, P Verderio, A De Paoli, A Ferraro… - Annals of oncology, 2013 - Elsevier
Background To explore correlation between the quality of surgery and outcome in high-risk
soft tissue sarcoma (STS) patients treated within a phase III randomized trial. Patients and
Methods In the trial, all patients received three cycles of preoperative chemotherapy (CT)
with epirubicin 120 mg/m 2 and ifosfamide 9 g/m 2 and were randomly assigned to receive
two further postoperative cycles. Radiotherapy (RT) could be delivered in the preoperative
or postoperative setting. The association between surgical margins and overall survival (OS) …
soft tissue sarcoma (STS) patients treated within a phase III randomized trial. Patients and
Methods In the trial, all patients received three cycles of preoperative chemotherapy (CT)
with epirubicin 120 mg/m 2 and ifosfamide 9 g/m 2 and were randomly assigned to receive
two further postoperative cycles. Radiotherapy (RT) could be delivered in the preoperative
or postoperative setting. The association between surgical margins and overall survival (OS) …
